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Since the discovery of the endocannabinoid system in the late eighties, there have been thousands of studies published in medical journals detailing the effects of cannabinoids on the body.
Not hempseed oil
Full-spectrum hemp oil is not the hempseed oil you typically find in the grocery store. Hemp oil is derived from whole hemp plant strains, while hempseed oil is derived only from hemp seeds and contains no cannabinoids.
Our bodies naturally create cannabinoids called Anandamide and 2-AG. Like phytocannabinoids, the body's endocannabinoids help with maintaining homeostasis; your body's natural state of stability.
A phytocannabinoid is a molecule synthesized by plants. There are 113 known phytocannabinoids in the cannabis plant, including CBD and CBG. Phytocannabinoids are used to treat a number of human and animal ailments.
The endocannabinoid system or "ECS" consists of the endogenous cannabinoids (or endocannabinoids), and it also consists of cannabinoid receptors and the enzymes that synthesise and degrade endocannabinoids. Many of the effects of cannabinoids and endocannabinoids are mediated by two G protein-coupled receptors (known as GPCRs), CB and CB, although additional receptors may be involved. CB receptors are present in very high levels in several brain regions and in lower amounts in a more widespread fashion. These receptors mediate many of the psychoactive effects of cannabinoids. CB receptors have a more restricted distribution, being found in a number of immune cells and in a few neurones. Both CB and CB couple primarily to inhibitory G proteins and are subject to the same pharmacological influences as other GPCRs. Thus, partial agonism, functional selectivity and inverse agonism all play important roles in determining the cellular response to specific cannabinoids.
CBD or "Cannabidiol" has a multitude of health benefits on its own. Studies have shown that CBD can help reduce chronic pain by impacting endocannabinoid receptor activity, reducing inflammation and interacting with neurotransmitters (4Trusted Source).
For example, one study in rats found that CBD injections reduced pain response to surgical incision, while another rat study found that oral CBD treatment significantly reduced sciatic nerve pain and inflammation (5Trusted Source, 6Trusted Source).
Several human studies have found that a combination of CBD and THC is effective in treating pain related to multiple sclerosis and arthritis.
CBD has also been shown to strengthen and improve the efficiency of mitochondria, the "powerhouses" of your cells that are responsible for ensuring that your cells work the way they should. Research on the ECS has shown that as part of regulating homeostasis, and is responsible for repairing damaged cells. Research has also shown that cannabinoids are able to target damaged cells while sparing normal cells, meaning that the Endocannabinoid system may act as a biological defense system.
When a person ingests Hemp CBD Oil or other cannabinoids, these cannabinoid receptors are activated (CBD appears to have a greater affinity for CB2 receptors than CB1 receptors). Research indicates that when you supplement your ECS with non-toxic, non-habit-forming cannabinoids, you may create a healthier endocannabinoid system and, almost certainly, a healthier you.
Full Spectrum CBD
Uses the whole plant and contains trace amounts (less than 0.3%) of THC and other cannabinoids that might well enhance the overall CBD effect on the body.
A THC-free alternative that contains no trace amounts of other cannabinoids for those people who prefer to avoid even the most minute traces of THC.
As to which one is best for you is merely a matter of preference. Some people want to avoid any THC altogether, however minimal. And others prefer to gain what's known as the entourage effect of using Full Spectrum CBD.
Broad spectrum CBD
Broad spectrum CBD is a bit of a mix between full spectrum CBD and CBD Isolate. Like full spectrum, the other compounds found within the plant are preserved in the extract; however, like CBD Isolate, THC is completely removed.
The Entourage Effect
Research studies are showing that Full Spectrum CBD carries a host of other cannabinoids, which may create an "entourage effect" that works optimally with the human body's natural endocannabinoid system. For the sake of analogy, Full Spectrum CBD interacts with other cannabinoids much the same way vitamins are more effectively absorbed from whole foods sources than isolates.
Other Important Cannabinoids:
CBG or "Cannabigerol" displays a multitude of potential health benefits including working as a neuroprotectant, having antioxidant properties, aiding with skin ailments as an antibacterial and antifungal agent, appetite stimulation, treatment of gastrointestinal disorders, inflammation reduction, shows promise in fighting cancer, and lowering intraocular pressure, which may benefit glaucoma patients.
CBN or "Cannabinol" is considered a mildly psychoactive cannabinoid known for its powerful sedative properties. When THC is oxidized, the degradation process converts THC to CBN, which may account for the sedative effect aged cannabis often carries.
CBN shares a very similar chemical composition to THC and is thought to primarily bind with the CB2 receptor, but may also interact with the CB1 receptor. CBN acts an agonist to the TRPV2 receptor, a naturally producing protein that regulates several biological systems in the human body. This makes CBN potentially effective for combatting pain and inflammation, bone health, controlling convulsant behavior, lowering blood pressure, and treating skin conditions.
Higher levels of CBN in any cannabis product may provide a particularly effective option for battling insomnia and reducing anxiety. CBN may also be most effective for inducing sleep in combination with other cannabinoids such as THC and CBD.